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Leading HPLC Column OEM Manufacturer
Bulk Order / Small Order / OEM Service
From Factory Directly
✔ Ultra-smooth 0.08 μm inner surface
✔ Consistent batch-to-batch reproducibility
✔ Competitive factory price & Fast delivery
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Facing Problems with Your Current HPLC Columns?
❌ Peak tailing and poor resolution
❌ Unstable performance and short lifetime
❌ High pricing from imported brands
❌ Slow lead time and limited customization
👉 uHPLCs helps you solve ALL these issues.
1. Ultra-smooth Inner Surface (0.08 μm)
Sharper peaks, reduced dead volume, excellent reproducibility.
2. Precision Manufacturing from Tube to Packing
Strict QC ensures consistent performance across batches.
3. Complete Column Portfolio
C18/C8, HILIC, Chiral, SEC, Prep, Semi-prep, UPLC.
Standard HPLC Column Sizes & OEM Custom Options
We provide standard HPLC column sizes like 4.6×250, 4.6×150, 3.0×100, and 2.1×100 mm, and also support custom and OEM dimensions to fit your specific analytical needs.
C18 Columns
✔ High resolution for complex mixtures
✔ Stable retention & peak symmetry
✔ Reliable for pharma & QC methods
C8 Columns
✔ Shorter retention for fast runs
✔ Ideal when C18 is too strong
✔ Boosts throughput & efficiency
Normal Phase HPLC Column
✔ Better separation of polar compounds
✔ Stable in non-aqueous systems
✔ Solves isomer & impurity challenges
SEC Columns
✔ Accurate size-based separation
✔ Low adsorption for clean results
✔ Ideal for polymers & aggregates
Bio-SEC Columns
✔ High recovery of sensitive proteins
✔ Superior resolution for biomolecules
✔ Perfect for mAbs & biologics QC
PFP Columns
✔ Excellent selectivity for isomers
✔ Strong π-π & polar interactions
✔ Solves difficult aromatic separations
Phenyl Column
✔ Precise aromatic compound separation
✔ Strong π-π interaction selectivity
✔ Reduces tailing in complex matrices
Preparative Columns
✔ High loading for large-scale purification
✔ Durable hardware under high flow
✔ Consistent purity at production scale
Guard Column
✔ Protects main column from contamination
✔ Extends column lifetime significantly
✔ Saves cost on replacements
Ghost Buster Column
✔ Eliminates ghost peaks effectively
✔ Stabilizes baseline & reduces noise
✔ Essential for LC-MS trace analysis
Peak Smooth Column
✔ Sharper peaks, less tailing
✔ Enhanced packing uniformity
✔ Improves quantification accuracy
Technical Specifications – HPLC Columns
| Parameter | Specification |
|---|---|
| Surface Roughness (ID) | 0.08 μm ultra-smooth inner wall |
| Material (Column Tube) | High-precision 316L stainless steel (anti-corrosion, high pressure) |
| Bonding Technology | Unique bonding process; double end-capping for stability |
| Particle Sizes | 1.7 μm / 3 μm / 5 μm / 10 μm |
| Pore Size Options | 100 Å / 120 Å / 300 Å（Bio-SEC, peptides, proteins） |
| Pressure Rating | Up to 1200 bar（depending on ID & length） |
| Available Column IDs | 2.1 mm / 3.0 mm / 4.0 mm / 4.6 mm / 7.8 mm / 10 mm / 20mm / 30mm/ 50mm ~ |
| Available Lengths | 20 / 30 / 50 / 75 / 100 / 150 / 250 / 300 mm（customizable） |
| End-Fitting Type | Standard / Direct-connect (PEEK disc, SS frit, PEEK cap types available) |
| Packing Options | C18, C8, HILIC, Polar-embedded, CN, Phenyl, PFP, SEC, Bio-SEC（all optional） |
| USP L Classification | C18 (L1), C8 (L7), Phenyl (L11), CN (L10), HILIC (L3/L68), PFP (L43) |
| pH Range (Typical) | pH 2–8 / 1–11 / 2–9 depending on chemistry（C18、C8、Bio、HILIC） |
| Key Performance Features | High batch-to-batch reproducibility、strong retention、excellent peak shape |
| Applications | Pharmaceuticals, food safety, TCM, environmental, biologics, metabolites detection |
Your Reliable HPLC Column OEM Partner
Work with 100+ Global Laboratories, Brands & Universities
SERVICES
Custom HPLC Column Design
Tailor-made columns to fit your specific method, dimension, and stationary phase requirements — from analytical to preparative scale.
OEM & Private Label Manufacturing
Comprehensive OEM solutions with custom branding, labeling, and packaging for global distributors and instrument brands.
Technical Support & Method Consultation
Our chromatography experts provide full support for column selection, method optimization, and troubleshooting.
Fast Delivery
& Global Shipping
Efficient production and worldwide logistics ensure reliable delivery of samples and bulk orders on time, every time.
WHY US
uHPLCs manufactures high-quality HPLC columns engineered for precise, reliable, and efficient chromatographic separation.
Each column is built with superior packing technology and strict quality control to ensure reproducible performance in analytical and semi-preparative applications.
🔹 1. Precision Manufacturing
All columns are produced in our ISO-certified facility with strict process control — ensuring consistent quality, purity, and reproducibility.
🔹 2. Proven Performance
Advanced packing technology delivers high column efficiency, low back pressure, and stable retention for reliable analytical results.
🔹 3. Custom & OEM Solutions
From C18 to specialty phases, we provide tailored dimensions, private-label branding, and fast delivery for global laboratories and instrument makers.
How We Control
Production & Quality
🔹 1. Precision In-House Manufacturing
From silica bonding to column packing, every step is completed in our ISO-certified facility to ensure uniformity and stable performance.
🔹 2. Strict Performance Testing
Each batch is tested for theoretical plates, peak symmetry, retention time, and pressure stability, resulting in an ultra-low failure rate.
🔹 3. Certified Quality & Traceability
All columns ship with COA and test reports, backed by ISO 9001, CE, and RoHS compliance for global laboratory use.
What makes uHPLCs different from other HPLC column manufacturers?
At uHPLCs, every column is produced in-house under strict ISO-certified quality control — from silica synthesis to final end-capping.
Our proprietary packing technology ensures consistent efficiency, reproducibility, and long-term stability that rival leading international brands.
Can I order custom or OEM HPLC columns?
Yes. We provide OEM and fully customized HPLC columns, including dimensions, stationary phases, particle sizes, labeling, and packaging.
Our engineering team supports private-label solutions for instrument manufacturers, distributors, and research laboratories.
What stationary phases and particle sizes are available?
We offer a wide range of stationary phases — C18, C8, CN, Phenyl, HILIC, Silica, Amino, and more — with particle sizes from 1.8 µm to 10 µm.
Both analytical and semi-preparative formats are available to meet various method requirements.
Are uHPLCs columns compatible with all major HPLC systems?
Yes. Our columns use industry-standard fittings (10-32 UNF, 1/16” tubing) and are fully compatible with Agilent, Waters, Shimadzu, Thermo Fisher, and other major HPLC instruments.
How do you ensure quality and reproducibility?
Each batch is tested for theoretical plates, peak symmetry, and retention time using standard compounds.
Every column ships with a Certificate of Analysis (COA) and performance report to guarantee traceable, reproducible results.
CLIENT TESTIMONIALS
uHPLCs columns deliver excellent peak shape and reproducibility across our QC and R&D workflows.
Their consistency and technical support have helped us optimize several critical assays.
Maria Rodriguez
We switched to uHPLCs columns for our peptide analysis and immediately noticed improved resolution and reduced back pressure.
The quality is on par with leading global brands, but with faster delivery and great customization options.
William Hayes
As an OEM partner, uHPLCs has been incredibly reliable — from product quality to on-time shipments.
Their team understands both technical and commercial needs, making collaboration seamless. Good Job, you can try to work with them.
Samantha Lee
Trusted HPLC Columns,
Tailored for Your Lab.
Fast delivery, consistent quality, and global OEM support from uHPLCs — the column manufacturer behind precise results.