From Factory Directly
✔ Extends main column lifetime 3–10×
✔ No impact on peak shape or separation
✔ Compatible with Agilent / Waters / Shimadzu systems
✔ OEM-ready design for private label & replacement projects
A guard column is the cheapest insurance for every HPLC system.
Item: P3K0B00272
1.Cartridge Size Option:
5μ / 3μ / 2μ / 1.8μ
2.Cartridge Option:
Reversed Phase / HILIC
Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.
Item: P3K0B-00148
1.Cartridge Size Option:
5μ / 3μ / 2μ / 1.8μ
2.Cartridge Option:
Reversed Phase / HILIC /Normal Phase/SEC
Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.
Item: P3K0B-00275 ( SS )
Item: P3K0B-00099 ( peek)
1.Cartridge Size Option:
5μ / 3μ / 2μ / 1.8μ
2.Cartridge Option:
Reversed Phase / HILIC /Normal Phase/SEC
Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.
Item: P3K0B-00280
1.Cartridge Size Option:
5μ / 3μ / 2μ / 1.8μ
2.Cartridge Option:
Reversed Phase / HILIC /Normal Phase/SEC
Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.
Item: P3K0B-00148
1.Cartridge Size Option:
5μ / 3μ
2.Cartridge Option:
Reversed Phase / HILIC / Normal Phase / SEC
Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.
Item: P3K0B-00075
1.Cartridge Size Option:
5μ / 3μ / 3.5μ
2.Cartridge Option:
Reversed Phase / HILIC / Normal Phase / SEC
Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.
Item: P3K0B-00209
1.Cartridge Size Option:
10μ / 5μ
2.Cartridge Option:
General Type C18 / Pure Water-resistant C18
Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.
Item: P3K0B-00060
1.Cartridge Size Option:
10μ / 5μ
2.Cartridge Option:
General Type C18 / Pure Water-resistant C18
Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.
Item: P3K0B-00265
1.Cartridge Size Option:
10μ / 5μ
2.Cartridge Option:
General Type C18 / Pure Water-resistant C18
Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.








Installing the uHPLCs Guard Protection System is seamless and efficient:
Tailored guard column dimensions, fittings, frits, and materials to match your HPLC system and application requirements.
Full private labeling support including logo engraving, packaging, and documentation — ready for OEM and distributor brands.
Every guard column is produced under ISO-controlled processes with performance testing to ensure stable protection and repeatability.
Direct access to chromatography engineers for selection guidance, compatibility checks, and troubleshooting support.
OEM buyers choose uHPLCs for reliable guard columns that protect main columns, reduce operating cost, and support long-term OEM supply.
✔ Low Dead Volume, Stable Performance
No peak distortion. No method revalidation.
✔ Consistent Batch-to-Batch Quality
Reliable performance across repeat and volume orders.
✔ OEM-Ready Replacement for Major Brands
Compatible with Agilent, Waters, Phenomenex systems.
✔ Long-Term OEM Supply, Not One-Off Sales
Built for continuous production and stable lead times.
Still unsure which guard column fits your method?
👉 Talk to our OEM engineer for a fast recommendation.
An HPLC guard column protects your analytical or preparative column by trapping particulates, matrix residues, strongly retained compounds, and sample impurities before they reach the main column.
By preventing contamination, pressure buildup, and irreversible fouling, a guard column significantly extends column lifetime, stabilizes system pressure, and maintains consistent chromatographic performance.
When properly selected, a guard column does not negatively affect peak shape or separation.
uHPLCs guard columns are designed with low dead volume and matched stationary phases, ensuring minimal band broadening and excellent peak symmetry.
In many cases, users actually see more stable retention times and improved reproducibility due to reduced contamination of the analytical column.
Yes. uHPLCs guard columns are fully compatible with Agilent, Waters, Shimadzu, and other major HPLC / UHPLC systems.
We offer multiple connection types, column dimensions, and cartridge formats to match original equipment standards, making our guard columns ideal for OEM replacement, private labeling, and brand substitution projects.
Yes. OEM and customization are core strengths of uHPLCs.
We support custom guard column solutions including:
Column dimensions and housing designs
Stationary phase matching (C18, C8, HILIC, SEC, etc.)
Private labeling, branding, and packaging
Cartridge-style or integrated guard designs
Our OEM services are designed to help brands and laboratories achieve consistent performance, supply stability, and competitive cost control.
For standard guard column models, samples can typically be delivered within 3–7 days.
OEM or customized guard columns usually have a lead time of 7–15 days, depending on specifications and order volume.
Our in-house manufacturing and quality control allow us to support fast prototyping, reliable scaling, and long-term supply continuity for OEM buyers.
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