uHPLCs HIPSOUL

HPLC Guard Columns That Protect Your Main Column & Cut Costs

Extend column lifetime · Reduce contamination · OEM-ready

From Factory Directly 

✔ Extends main column lifetime 3–10×

✔ No impact on peak shape or separation

✔ Compatible with Agilent / Waters / Shimadzu systems

✔ OEM-ready design for private label & replacement projects

Talk to OEM Engineer (24h Reply)

Why Most HPLC Columns Fail Too Early

A guard column is the cheapest insurance for every HPLC system.

Key Benefits:

  • Extends Column Lifetime
    Reduces contamination and irreversible fouling.
  • Maintains Peak Quality
    Low dead volume design preserves peak shape and resolution.
  • Reduces Operating Cost
    Fewer replacements, less downtime, lower consumable spend.
  • System-Compatible & Easy to Install
    Works with major HPLC systems without method changes.

Direction Guard Column

Standard Guard Column

Guard Cartridges

Preparation Guard Column

Not Sure Which Guard Column Fits Your Application?

👉 Talk to Our OEM Engineer

① Analytical HPLC Guard Column

  • Routine HPLC analysis
  • Protect analytical columns
  • Compatible with Agilent / Waters

Item: P3K0B00272
1.Cartridge Size Option:
5μ / 3μ / 2μ / 1.8μ
2.Cartridge Option: 
Reversed Phase / HILIC

Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.

Item: P3K0B-00148
1.Cartridge Size Option:
5μ / 3μ / 2μ / 1.8μ
2.Cartridge Option: 
Reversed Phase / HILIC /Normal Phase/SEC

Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.

Item: P3K0B-00275 ( SS ) 
Item: P3K0B-00099 ( peek)
1.Cartridge Size Option:
5μ / 3μ / 2μ / 1.8μ
2.Cartridge Option: 
Reversed Phase / HILIC /Normal Phase/SEC

Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.

Item: P3K0B-00280
1.Cartridge Size Option:
5μ / 3μ / 2μ / 1.8μ
2.Cartridge Option: 
Reversed Phase / HILIC /Normal Phase/SEC

Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.

Item: P3K0B-00148
1.Cartridge Size Option:
5μ / 3μ 
2.Cartridge Option: 
Reversed Phase / HILIC / Normal Phase / SEC

Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.

Item: P3K0B-00075
1.Cartridge Size Option:
5μ / 3μ / 3.5μ
2.Cartridge Option: 
Reversed Phase / HILIC / Normal Phase / SEC

Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.

② Preparative HPLC Guard Column

  • High sample load
  • Large flow systems
  • Scale-up applications

Item: P3K0B-00209
1.Cartridge Size Option:
10μ / 5μ 
2.Cartridge Option: 
General Type C18 / Pure Water-resistant C18

Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.

Item: P3K0B-00060
1.Cartridge Size Option:
10μ / 5μ 
2.Cartridge Option: 
General Type C18 / Pure Water-resistant C18

Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.

Item: P3K0B-00265
1.Cartridge Size Option:
10μ / 5μ 
2.Cartridge Option: 
General Type C18 / Pure Water-resistant C18

Choose guard cartridges with
C18, C8, Phenyl, Bio-SEC, or
HILIC-SiO2 to enhance your
analytical results.

③ HPLC Guard Cartridges

2.1 UHPLC Cartridge Stainless Steel Super High Pressure

2.1 Peek UHPLC Cartridge for Analytical Guard Cartridges

Peek 3.0 HPLC Cartridge for Analytical Guard Cartridges

4.6 Peek HPLC Cartridge, HPLC Column Assembly for sale

4.6 Peek HPLC Cartridge with Stainless Steel Frit

10.0 Peek HPLC Cartridge with Stainless Steel Frit

21.2 Stainless Steel HPLC Cartridge for Prep HPLC Guard Column

30.0 Stainless Steel HPLC Cartridge for for Prep HPLC Guard Column

Why OEM Buyers Switch from
Agilent / Phenomenex to uHPLCs

Innovative design to help Compatible Most of HPLC Fittings

Installing the uHPLCs Guard Protection System is seamless and efficient:

  • Easy Installation: Simply attach to your preferred column; no complex setup required.
  • Floating Outlet Design: Automatically adjusts to match the precise depth of columns from nearly any manufacturer.
  • Low Dead Volume: Optimizes performance by minimizing dead volume.
  • Leak-Free Connection: Ensures a secure, leak-free seal without the need for unions or adapters.
  • Universal Compatibility: Suitable for use with columns from various manufacturers, ensuring versatility across different systems.

Top Hardware HPLC,UHPLC Consumables Supplier
Work with 100+ Brands & University

Guard Column OEM Services

OEM Custom Specifications

Tailored guard column dimensions, fittings, frits, and materials to match your HPLC system and application requirements.

Private Label & Branding

Full private labeling support including logo engraving, packaging, and documentation — ready for OEM and distributor brands.

Strict Batch-to-Batch Consistency

Every guard column is produced under ISO-controlled processes with performance testing to ensure stable protection and repeatability.

Engineer-Level Technical Support

Direct access to chromatography engineers for selection guidance, compatibility checks, and troubleshooting support.

Why OEM Buyers Switch to uHPLCs

OEM buyers choose uHPLCs for reliable guard columns that protect main columns, reduce operating cost, and support long-term OEM supply.

Low Dead Volume, Stable Performance
No peak distortion. No method revalidation.

Consistent Batch-to-Batch Quality
Reliable performance across repeat and volume orders.

OEM-Ready Replacement for Major Brands
Compatible with Agilent, Waters, Phenomenex systems.

Long-Term OEM Supply, Not One-Off Sales
Built for continuous production and stable lead times.

Trusted by OEM Buyers & Laboratories

“uHPLCs guard columns significantly reduced contamination issues and extended the lifetime of our analytical columns. Batch-to-batch consistency has been excellent for routine QC work.”
Maria Rodriguez
Analytical Laboratory Manager
“We use uHPLCs guard columns as an OEM solution for our private label program. Performance consistency, customization flexibility, and reliable supply have made them a long-term partner.”
William Hayes
OEM Product Manager

FAQ

HPLC Guard Column (OEM Buyers)

Still unsure which guard column fits your method?
👉 Talk to our OEM engineer for a fast recommendation.

An HPLC guard column protects your analytical or preparative column by trapping particulates, matrix residues, strongly retained compounds, and sample impurities before they reach the main column.

By preventing contamination, pressure buildup, and irreversible fouling, a guard column significantly extends column lifetime, stabilizes system pressure, and maintains consistent chromatographic performance.

When properly selected, a guard column does not negatively affect peak shape or separation.

uHPLCs guard columns are designed with low dead volume and matched stationary phases, ensuring minimal band broadening and excellent peak symmetry.
In many cases, users actually see more stable retention times and improved reproducibility due to reduced contamination of the analytical column.

Yes. uHPLCs guard columns are fully compatible with Agilent, Waters, Shimadzu, and other major HPLC / UHPLC systems.

We offer multiple connection types, column dimensions, and cartridge formats to match original equipment standards, making our guard columns ideal for OEM replacement, private labeling, and brand substitution projects.

Yes. OEM and customization are core strengths of uHPLCs.

We support custom guard column solutions including:

  • Column dimensions and housing designs

  • Stationary phase matching (C18, C8, HILIC, SEC, etc.)

  • Private labeling, branding, and packaging

  • Cartridge-style or integrated guard designs

Our OEM services are designed to help brands and laboratories achieve consistent performance, supply stability, and competitive cost control.

For standard guard column models, samples can typically be delivered within 3–7 days.
OEM or customized guard columns usually have a lead time of 7–15 days, depending on specifications and order volume.

Our in-house manufacturing and quality control allow us to support fast prototyping, reliable scaling, and long-term supply continuity for OEM buyers.

Talk to an HPLC Guard Column Specialist

Phone: +86 0755 28502380
51-3, Fu 'an West Road, Pinghu Street, Longgang District, Shenzhen City, 518111 China
We Will Send Back Your Inquiry Within 48-Hours

Can’t Get Enough?

Get More Information and Quotation
for Our HPLC Column Hardware Today !

Subscribe for exclusive offers and updates on new arrivals