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Revolutionary 2.1mm UHPLC Direct-Connect Guard Column Hardware

Boost your UHPLC performance with the 2.1mm Direct-Connect Guard Column – superior protection, refined separation.

  • Enhanced Performance: Smaller particle sizes ensure superior separation quality.
  • Direct-Connect Design: Simplifies installation, reducing downtime and maintenance effort.
  • Superior Protection: Effectively filters out contaminants, extending the lifespan of your main analytical column.
  • Cost-effective: By protecting your main column, it can significantly reduce long-term replacement and maintenance costs.
  • Versatile: Compatible with a wide range of UHPLC systems, facilitating broader use across different equipment.
  • Compact Size: The 2.1mm size reduces solvent usage without compromising performance, making it environmentally friendly and cost-efficient.

Features and Applications:


  1. Two-Part PEEK/Stainless Steel HolderThis hand-tight holder, made of PEEK and stainless steel, ensures durability and excellent chemical resistance.

  2. No Extra Tubing or Fittings Required: The design allows the holder to be connected directly to the column without the need for additional components.

  3. Universal Compatibility: The holder automatically adjusts to fit columns from any manufacturer, enhancing its versatility.

  4. Zero Dead Volume (ZDV) Connection: Ensures a perfect repeat connection with no loss in efficiency, improving chromatographic performance.

  5. Minimal Impact: The holder does not affect the efficiency of the column, ensuring reliable and consistent results.

  6. Convenient Cartridge Change: The holder remains plumbed when changing cartridges, simplifying maintenance and reducing downtime.

  7. Compatibility with 2.1mm uHPLC Cartridges: Specifically designed to be used with 2.1mm uHPLC cartridges, optimizing its performance with ultra-high pressure systems.

UHPLC Direct-Connect Trap 2.1mm Guard Column details


  1. Pharmaceutical Analysis: Can be used for separation of complex pharmaceutical mixtures, ensuring drug quality and safety.

  2. Biotechnology: Useful for separating large and complex molecules in the biotech industry, including proteins and peptides.

  3. Environmental Testing: Enables the analysis of complex environmental samples, detecting contaminants at very low concentrations.

  4. Food and Beverage Testing: Can separate compounds in food and beverages for quality control and safety assurance.

  5. Academic Research: A valuable tool in various research areas, including drug discovery, metabolomics, proteomics, and more.

Direct Connect HPLC Inline Filter

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