USHD SEC-Bio 1.8μm HPLC SEC Columns Factory Supplier
USHD Bio-SEC Column (1.8μm, 300Å) is a high-resolution size exclusion chromatography column specifically designed for the analysis of macromolecular biological samples. It is ideal for applications such as protein, nucleic acid, enzyme, antibody, peptide, and ADC drug molecular weight analysis—including monoclonal antibody (mAb) development. With a specialized bonding process and ultra-low adsorption, it ensures accurate results, longer column life, and stable performance.
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Features:
- Targeted for Biomolecular Analysis: Suitable for proteins, nucleic acids, peptides, enzymes, antibodies, and ADC drugs.
- Supports mAb Drug Development: Optimized for high-precision molecular weight analysis of therapeutic biologics.
- High Resolution (1.8μm Particle Size): Delivers sharp peaks and excellent separation performance for complex biological samples.
- Ultra-Low Adsorption Surface: Reduces interaction with sensitive biomolecules for improved accuracy.
- Special Bonding Technology: Minimizes dead adsorption and significantly extends chromatographic column life.
- Excellent Reproducibility: Stable batch-to-batch performance ensures consistent analytical results.
- Molecular Weight Range Compatibility:
- Globular proteins: 500 – 1,250,000 Da
- Wide pH Range: Operates effectively within pH 2–8, suitable for various biopharmaceutical conditions.
Specifications
| Property | USHD Bio-SEC 1.8μm Series |
|---|---|
| USP | L33 / L59 |
| Pore Size Option | 1.8µm, 300 Å |
| Surface Area (m²/g) | / |
| Carbon Load (%) | / |
| pH Tolerance Range | 2-8 |
| Column Specifications | 4.6× 300 mm 4.6 ×150 mm |
| Features and Applications |
|
Analytical column, C18 bonded phase, C18 chromatography, C18 column, C18 HPLC column, C18 stationary phase, Chromatography column, Column packing material, High performance liquid chromatography, HPLC analysis, HPLC column, HPLC separation, Liquid chromatography column, Reverse phase column, Silica-based column
Column body
This is a measure of the distribution of particles packed in a column. In HPLC, it is preferable to have narrow particle size distribution as a narrow particle size distribution can lead to better HPLC column efficiency.
Endcap
In LC chromatography the reaction of a silylating agent with unreacted accessible silanols remaining on the silica gel surface after the initial bonding reaction of the HPLC column stationary phase. HPLC column endcapping eliminates unwanted secondary silanol interactions between compounds and the stationary phase.
PEEK frit
Longer filtration life
Consistent frit-to-frit swept volumes
Biocompatible and inert to most solvents
Suitable for low and high pressure applications.
Enhanced sealing and excellent chemical resistance.
PEEK frits can be used up to 80 ºC.
All Hot Sale HPLC Columns
Select ideal HPLC column for your lab applications based on factors like separation efficiency, pore size, pH tolerance, and specifications.
| Item | USP | Pore Size Option | Surface area (m²/g) | Carbon Load (%) | PH Tolerance Range | Column Specifications |
|---|---|---|---|---|---|---|
|
USHD C18-Pro |
L1 |
5μm, 150A 3.5μm, 150A |
200 |
10 |
2-8 |
4.6X250mm 4.6X150mm 4.6X100mm 4.6X50mm 3.0X100mm 3.0X50mm 2.1X100mm 2.1X50mm |
|
USHD C18 |
L1 |
5μm, 120A 3μm, 120A 1.8μm, 120A |
320 |
17 |
2-8 |
4.6X250mm 4.6X150mm 4.6X100mm 4.6X50mm 3.0X100mm 3.0X50mm 2.1X100mm 2.1X50mm |
|
USHD C18-AQ |
L1 |
5μm, 120A 3μm, 120A 1.8μm, 120A |
320 |
12 |
2-8 |
4.6X250mm 4.6X150mm 4.6X100mm 4.6X50mm 3.0X100mm 3.0X50mm 2.1X100mm 2.1X50mm |
|
USHD C18-AR |
L1 |
5μm, 120A 3μm, 120A 1.8μm, 120A |
320 |
10 |
0.5-8 |
4.6X250mm 4.6X150mm 4.6X100mm 4.6X50mm 3.0X100mm 3.0X50mm 2.1X100mm 2.1X50mm |
|
USHD C18-T |
L1 |
5μm, 120A 3μm, 120A 1.8μm, 120A |
320 |
14 |
1-11 |
4.6X250mm 4.6X150mm 4.6X100mm 4.6X50mm 3.0X100mm 3.0X50mm 2.1X100mm 2.1X50mm |
|
USHD C8-PRO |
L7 |
5μm, 150A 3.5μm, 150A |
200 |
7 |
2-8 |
4.6X250mm 4.6X150mm 4.6X100mm 4.6X50mm 3.0X100mm 3.0X50mm 2.1X100mm 2.1X50mm |
|
USHD C8 |
L7 |
5μm, 150A 3.5μm, 120A 1.8μm, 120A |
320 |
12 |
2-8 |
4.6X250mm 4.6X150mm 4.6X100mm 4.6X50mm 3.0X100mm 3.0X50mm 2.1X100mm 2.1X50mm |
Analytical and Semi-Prep HPLC Column Size Option
Specification（ Customizable）/ Size | Materials | Applications |
USHD C18-Pro ×30mm ; 2.1×50mm ; 2.1×75mm ; 2.1×100mm ; 2.1×125mm ; 2.1×150mm; 2.1×200mm ; 2.1×250mm ; 2.1×300mm | 316L Stainless Steel | Analytical |
3.0 ×30mm ; 3.0×50mm ; 3.0×75mm ; 3.0×100mm ; 3.0×125mm ; 3.0×150mm ； 3.0×200mm ; 3.0×250mm ; 3.0×300mm ; | 316L Stainless Steel | Analytical |
4.0×20mm ; 4.0×30mm ; 4.0×50mm ; 4.0×100mm 4.0×150mm ; ; 4.0×200mm； 4.0×250mm ; 4.0×300mm | 316L Stainless Steel | Analytical |
4.6×20mm ; 4.6×30mm ; 4.6×50mm ; 4.6×100mm 4.6×150mm ; 4.6×200mm ; 4.6×250mm ; 4.6×300mm | 316L Stainless Steel | Analytical |
7.8×150mm ; 7.8×250mm ; 7.8×300mm | 316L Stainless Steel | Semi-prep |
10×50mm ; 10×100mm ; 10×150mm 10×200mm ; 10×250mm ; 10×300mm | 316L Stainless Steel | Semi-prep |
20×50mm ; 20×100mm ; 20×150mm ; 20×200mm 20×250mm ; 20×300mm | 316L Stainless Steel | Semi-prep |
21.2×150mm ; 21.2× 250mm | 316L Stainless Steel | Semi-prep |
