USHD C18 HPLC Column
USHD C18 HPLC Column
USHD C18 is a reversed-phase USP L1 octadecyl column with 17% carbon, 320 m²/g, 120 Å and pH 2–8. Dual end-capping supports peak shape for acidic and basic compounds.
Listed particle sizes are 5 μm, 3 μm and 1.8 μm in standard analytical dimensions. For C18-Pro, C18-AQ, C18-AR or C18-T, return to the C18 HPLC Columns hub.
USHD C18 HPLC column
Features
USHD C18 is the higher-carbon USP L1 octadecyl phase for routine reversed-phase work.
- High carbon load — 17% carbon for stronger retention and selectivity than C18-Pro.
- 120 Å silica — 320 m²/g surface area for analytical reversed-phase methods.
- Dual end-capping — Published for peak shape of acidic and basic compounds and batch reproducibility.
- Particle sizes — 5 μm, 3 μm and 1.8 μm for HPLC and UHPLC formats.
Specifications
Published specifications for the USHD C18 series only.
| Phase | USP | Particle Size | Pore Size | Surface Area | Carbon Load | pH | Endcapping |
|---|---|---|---|---|---|---|---|
| USHD C18 | L1 | 5 μm, 3 μm, 1.8 μm | 120 Å | 320 m²/g | 17% | 2–8 | Dual end-capping |
Standard dimensions
Other internal diameters and lengths can be requested as a custom column.
| Particle Size | Pore Size | Standard Dimensions |
|---|---|---|
| 5 μm | 120 Å | 2.1×50 mm, 2.1×100 mm, 3.0×50 mm, 3.0×100 mm, 4.6×50 mm, 4.6×100 mm, 4.6×150 mm, 4.6×250 mm |
| 3 μm | 120 Å | 2.1×50 mm, 2.1×100 mm, 3.0×50 mm, 3.0×100 mm, 4.6×50 mm, 4.6×100 mm, 4.6×150 mm, 4.6×250 mm |
| 1.8 μm | 120 Å | 2.1×50 mm, 2.1×100 mm, 3.0×50 mm, 3.0×100 mm, 4.6×50 mm, 4.6×100 mm, 4.6×150 mm, 4.6×250 mm |
Applications
Higher carbon load for stronger retention and selectivity on routine reversed-phase methods.
Routine reversed phase
Pharmaceutical, food and environmental samples that need stronger C18 retention.
Method development
Start here when a general USP L1 C18 is required and C18-Pro retention is too low.
Need another selectivity?
Compare C18-Pro, C18-AQ, C18-AR and C18-T on the C18 HPLC Columns hub.
Too much retention?
See USHD C8 HPLC columns when analytes hold too long on C18.
Support
Send particle size, dimensions and quantity. We confirm the catalog number with the quote.
Quote checklist
Phase: USHD C18 · particle size · dimensions · quantity · destination
Family comparison
Still choosing among five C18 phases? Use the C18 HPLC Columns hub.
Custom sizes
Sizes outside the standard dimension list can be requested as a custom packed column.
FAQ
Answers for the USHD C18 series.
01 What is USHD C18 used for?
USHD C18 is the higher-carbon USP L1 phase in the HIPSOUL C18 family: 17% carbon, 320 m²/g, 120 Å, pH 2–8. It is used for routine reversed-phase methods that need stronger retention than C18-Pro.
02 What particle sizes and dimensions are listed?
USHD C18 is listed at 5 μm, 3 μm and 1.8 μm, 120 Å. Standard dimensions are 2.1×50, 2.1×100, 3.0×50, 3.0×100, 4.6×50, 4.6×100, 4.6×150 and 4.6×250 mm.
03 Does USHD C18 use dual end-capping?
Yes. The published USHD C18 product description includes dual end-capping for peak shape of acidic and basic compounds and batch-to-batch reproducibility.
04 How is USHD C18 different from C18-Pro, C18-AQ, C18-AR and C18-T?
Those are other USP L1 selectivities on the C18 HPLC Columns hub. C18-Pro is 10% carbon / 150 Å. C18-AQ is for high-water mobile phases. C18-AR is for low pH (0.5–8). C18-T is hybrid silica for pH 1–11.
05 When should I choose C8 instead?
C8 (USP L7) is less hydrophobic than C18 and is used when analytes retain too strongly on C18 or when a shorter run is needed.
Need a USHD C18 size matched to your method?
Request a USHD C18 Quote
Tell us the particle size, dimensions and quantity. We will confirm the catalog number and reply with availability and pricing.
Helpful to include:
- Phase: USHD C18
- Particle size and dimensions
- Mobile phase or current column brand
- Quantity and destination
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