Application-Specific Packed Columns
Specialty HPLC Columns
Dedicated HPLC packed columns for methods that a general-purpose phase does not fully cover. Current catalog: ValuSil C18 for USP L1 routine HPLC, and Hsol Amino for amino acid analysis.
- ValuSil C18 — USP L1, 1.8 / 3 / 5 μm, 120 Å
- Hsol Amino — amino-acid selective, 3 / 5 μm, 4.6 × 250 mm
- Documented catalog SKUs
- Custom / OEM dedicated packing on request
2 Catalog Families
USP L1 C18 (ValuSil)
Amino-Acid Dedicated (Hsol)
Custom / OEM Packing
Find the Right Specialty HPLC Column
Start with your method, then open the matching family or send an RFQ.
Step 1 — What are you analyzing?
USP L1 / C18 assaysAmino acids & derivativesOther dedicated method
Step 2 — Choose catalog family
Step 3 — Confirm size & particle
Not sure which family fits? Send your current column brand, method and detector — we will recommend ValuSil, Hsol Amino, or a custom packing. Get a recommendation →
Available Specialty HPLC Column Families
Only these two families are listed as current catalog specialty columns. Additional dedicated phases are quoted as custom packing.
ValuSil C18 Chromatography Column
Cost-effective octadecyl-bonded silica for routine reversed-phase HPLC that needs USP L1 classification and stable batch retention.
USP L11.8 / 3 / 5 μm120 ÅFully end-capped
- USP L1 C18, carbon load 16.4%, fully end-capped
- Particle sizes 1.8 μm, 3 μm and 5 μm, all 120 Å
- Batch retention-time RSD ≤ 1.5% in product documentation
Catalog SKUs: P1F0B-00916 to P1F0B-00908 (ten catalog sizes)
Hsol Amino Acid HPLC Column
Dedicated HPLC packing for natural and synthetic amino acids, including polar, ionizable species and isomers such as leucine / isoleucine.
Amino-acid selective3 / 5 μm120 ÅUV / FLD / PDA / MS
- Catalog format 4.6 × 250 mm, 3 μm and 5 μm, 120 Å
- pH 1.0–8.0, ≤ 40 MPa, typical max. 60 °C
- Compatible with UV, FLD, PDA and MS detectors
Catalog SKUs: P1F0B-00733 (3 μm), P1F0B-00726 (5 μm)
ValuSil C18 vs Hsol Amino
Use this table to pick a family. Open the product page for full specifications and chromatogram data.
| ValuSil C18 | Hsol Amino | |
|---|---|---|
| Primary job | USP L1 routine reversed-phase HPLC | Amino acid and derivative analysis |
| Stationary phase | Octadecyl-bonded silica (C18) | Amino-acid optimized silica packing |
| USP class | L1 | Not a USP L1 C18 column |
| Particle size | 1.8 / 3 / 5 μm | 3 / 5 μm |
| Pore size | 120 Å | 120 Å |
| Catalog format | 2.1–4.6 mm ID, 50–250 mm length | 4.6 × 250 mm |
| Typical samples | APIs, related substances, food additives, vitamins | Free amino acids, protein hydrolysates, feed amino acids |
| Start here | ValuSil C18 page | Hsol Amino page |
Match the Column to the Application
Practical routing from method intent to the correct specialty family.
Choose ValuSil C18 when
- The method specifies USP L1 / C18
- You need a cost-controlled replacement for routine QC HPLC
- Samples are typical reversed-phase assays (pharma QC, food screening, CRO throughput)
Choose Hsol Amino when
- The target is amino acids or common derivatives
- You need leucine / isoleucine or similar isomer resolution
- The workflow is food, feed, clinical or amino-acid API purity testing
How to Select a Specialty HPLC Column
Four practical checks connect method intent, family, catalog SKU and system constraints.
1
Confirm the Analytical Job
USP L1 / routine C18 assay, or amino acid / derivative separation.
2
Pick the Catalog Family
ValuSil C18 for L1 reversed-phase HPLC. Hsol Amino for amino-acid dedicated packing.
3
Match Size & Particle
Confirm ID × length and particle size against the listed product numbers.
4
Detector & Method Notes
For Hsol Amino, note derivatization (OPA / FMOC / PITC) and detector (UV / FLD / MS).
Need Help Matching a Specialty Column?
Send us:
- Current column brand / model
- ID × Length and particle size
- Method or USP class
- Analyte class / derivatization
- Detector (UV / FLD / PDA / MS)
- Quantity and destination
Custom Specialty HPLC Columns
If the method needs a dedicated packing that is not ValuSil C18 or Hsol Amino, we quote custom dimensions, particle size and stationary phase.
Do Not Assume Catalog Status
Other dedicated methods are quoted as custom until a product number is confirmed.
OEM / Private Label
Private-label and OEM packing available through OEM / custom.
Method Support
Share the current brand, pharmacopoeial method and detector so we can recommend packing and format.
Why Buy Specialty HPLC Columns From uHPLCs?
Application-matched packing, documented catalog SKUs, and a clear path from method to RFQ.
Method-Matched Families
ValuSil for USP L1 C18 work. Hsol Amino for amino-acid dedicated separations.
Documented Catalog SKUs
Listed product numbers for both families — no invented specialty codes.
Clear Custom Path
When the method is outside the catalog, RFQ for OEM packing instead of fake product pages.
Specialty HPLC Column FAQ
Practical answers for family selection, USP L1, amino-acid workflows and custom packing.
What is a specialty HPLC column?
A packed HPLC column optimized for a defined analytical job—such as USP L1 C18 methods or amino acid analysis—rather than a general-purpose phase catalog.
Which specialty columns are in the current catalog?
Two families: ValuSil C18 and Hsol Amino. Other dedicated phases are quoted as custom packing.
How do I choose between ValuSil C18 and Hsol Amino?
Use ValuSil C18 for USP L1 / routine reversed-phase HPLC. Use Hsol Amino when the analytes are amino acids or common derivatives. See the comparison table on this page.
Is Hsol Amino the same as an Amino NH2 column?
No. Hsol Amino is an amino-acid analysis column. An Amino NH2 HPLC column is an aminopropyl (NH2) bonded phase used for different separation modes.
Is ValuSil C18 USP L1 compliant?
Yes. Product documentation classifies ValuSil C18 as USP L1 octadecylsilane-bonded silica, fully end-capped, with 120 Å pores.
What Hsol Amino sizes are listed?
Catalog sizes are 4.6 × 250 mm, 3 μm (P1F0B-00733) and 5 μm (P1F0B-00726), both 120 Å. Additional sizes can be requested as custom.
Can uHPLCs make a custom specialty column?
Yes. Send method, current column, dimensions, particle size and quantity via the quote form or OEM / custom.
Related Resources
Continue to related HPLC column hubs and product pages.
Request a Specialty HPLC Column Quote
Tell us the family (ValuSil C18 or Hsol Amino), dimensions, particle size and quantity. For a custom dedicated phase, include the current brand and method.
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