USHD CN Normal Phase HPLC Column Factory Supplier
The USHD CN HPLC Column features an ultra-pure silica matrix bonded with a cyanopropyl stationary phase, offering dual-mode functionality for both normal and reversed-phase chromatography. With moderate polarity and unique π-electron interactions, it delivers distinct selectivity, making it ideal for separating strongly basic and highly hydrophobic compounds where traditional C18 or C8 columns fall short.
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Features:
USHD SiO₂ HPLC Analytical Column – Key Features
Cyanopropyl Bonded Phase: Provides moderate polarity for dual-use in normal and reversed-phase applications.
Distinct Selectivity: Offers different interaction profiles compared to C18 due to π-electron effects of the cyano group.
Excellent for Basic Compounds: Enhances peak shapes for strongly basic substances and supports high aqueous conditions.
Improved Elution of Hydrophobic Compounds: Ideal for analytes poorly eluted by standard reversed-phase columns.
High Purity Silica Matrix: Ensures consistent performance, efficiency, and peak symmetry across a wide pH range (2–8).
Specifications
| Property | USHD CN Normal Phase HPLC Analytical Column |
|---|---|
| USP | L3 |
| Pore Size Option | 5 µm, 120 Å |
| Surface Area (m²/g) | 320 |
| Carbon Load (%) | 7 |
| pH Tolerance Range | 2-8 |
| Column Specifications | 4.6 × 250 mm 4.6 × 150 mm 4.6 × 100 mm 4.6 × 50 mm 3.0 × 100 mm 3.0 × 50 mm 2.1 × 100 mm 2.1 × 50 mm |
| Features and Applications |
|
Analytical column, C18 bonded phase, C18 chromatography, C18 column, C18 HPLC column, C18 stationary phase, Chromatography column, Column packing material, High performance liquid chromatography, HPLC analysis, HPLC column, HPLC separation, Liquid chromatography column, Reverse phase column, Silica-based column
Column body
This is a measure of the distribution of particles packed in a column. In HPLC, it is preferable to have narrow particle size distribution as a narrow particle size distribution can lead to better HPLC column efficiency.
Endcap
In LC chromatography the reaction of a silylating agent with unreacted accessible silanols remaining on the silica gel surface after the initial bonding reaction of the HPLC column stationary phase. HPLC column endcapping eliminates unwanted secondary silanol interactions between compounds and the stationary phase.
PEEK frit
Longer filtration life
Consistent frit-to-frit swept volumes
Biocompatible and inert to most solvents
Suitable for low and high pressure applications.
Enhanced sealing and excellent chemical resistance.
PEEK frits can be used up to 80 ºC.
All Hot Sale HPLC Columns
Select ideal HPLC column for your lab applications based on factors like separation efficiency, pore size, pH tolerance, and specifications.
| Item | USP | Pore Size Option | Surface area (m²/g) | Carbon Load (%) | PH Tolerance Range | Column Specifications |
|---|---|---|---|---|---|---|
|
USHD C18-Pro |
L1 |
5μm, 150A 3.5μm, 150A |
200 |
10 |
2-8 |
4.6X250mm 4.6X150mm 4.6X100mm 4.6X50mm 3.0X100mm 3.0X50mm 2.1X100mm 2.1X50mm |
|
USHD C18 |
L1 |
5μm, 120A 3μm, 120A 1.8μm, 120A |
320 |
17 |
2-8 |
4.6X250mm 4.6X150mm 4.6X100mm 4.6X50mm 3.0X100mm 3.0X50mm 2.1X100mm 2.1X50mm |
|
USHD C18-AQ |
L1 |
5μm, 120A 3μm, 120A 1.8μm, 120A |
320 |
12 |
2-8 |
4.6X250mm 4.6X150mm 4.6X100mm 4.6X50mm 3.0X100mm 3.0X50mm 2.1X100mm 2.1X50mm |
|
USHD C18-AR |
L1 |
5μm, 120A 3μm, 120A 1.8μm, 120A |
320 |
10 |
0.5-8 |
4.6X250mm 4.6X150mm 4.6X100mm 4.6X50mm 3.0X100mm 3.0X50mm 2.1X100mm 2.1X50mm |
|
USHD C18-T |
L1 |
5μm, 120A 3μm, 120A 1.8μm, 120A |
320 |
14 |
1-11 |
4.6X250mm 4.6X150mm 4.6X100mm 4.6X50mm 3.0X100mm 3.0X50mm 2.1X100mm 2.1X50mm |
|
USHD C8-PRO |
L7 |
5μm, 150A 3.5μm, 150A |
200 |
7 |
2-8 |
4.6X250mm 4.6X150mm 4.6X100mm 4.6X50mm 3.0X100mm 3.0X50mm 2.1X100mm 2.1X50mm |
|
USHD C8 |
L7 |
5μm, 150A 3.5μm, 120A 1.8μm, 120A |
320 |
12 |
2-8 |
4.6X250mm 4.6X150mm 4.6X100mm 4.6X50mm 3.0X100mm 3.0X50mm 2.1X100mm 2.1X50mm |
Analytical and Semi-Prep HPLC Column Size Option
Specification（ Customizable）/ Size | Materials | Applications |
USHD C18-Pro ×30mm ; 2.1×50mm ; 2.1×75mm ; 2.1×100mm ; 2.1×125mm ; 2.1×150mm; 2.1×200mm ; 2.1×250mm ; 2.1×300mm | 316L Stainless Steel | Analytical |
3.0 ×30mm ; 3.0×50mm ; 3.0×75mm ; 3.0×100mm ; 3.0×125mm ; 3.0×150mm ； 3.0×200mm ; 3.0×250mm ; 3.0×300mm ; | 316L Stainless Steel | Analytical |
4.0×20mm ; 4.0×30mm ; 4.0×50mm ; 4.0×100mm 4.0×150mm ; ; 4.0×200mm； 4.0×250mm ; 4.0×300mm | 316L Stainless Steel | Analytical |
4.6×20mm ; 4.6×30mm ; 4.6×50mm ; 4.6×100mm 4.6×150mm ; 4.6×200mm ; 4.6×250mm ; 4.6×300mm | 316L Stainless Steel | Analytical |
7.8×150mm ; 7.8×250mm ; 7.8×300mm | 316L Stainless Steel | Semi-prep |
10×50mm ; 10×100mm ; 10×150mm 10×200mm ; 10×250mm ; 10×300mm | 316L Stainless Steel | Semi-prep |
20×50mm ; 20×100mm ; 20×150mm ; 20×200mm 20×250mm ; 20×300mm | 316L Stainless Steel | Semi-prep |
21.2×150mm ; 21.2× 250mm | 316L Stainless Steel | Semi-prep |
